Imaging of tumor angiogenesis in a novel skin chamber using MRI and optical imaging
نویسندگان
چکیده
Angiogenesis is an important process in the pathogenesis of tumors, and is thus a target for the development of novel approaches for cancer therapy. Non-invasive imaging methods can indicate changes in vessel morphology and function including tumor perfusion and permeability. Different imaging methods are used to assess vascularization, in particular MRI and optical imaging. Due to the complementary character of MRI and optical imaging, it is highly desirable to study angiogenesis with both imaging techniques simultaneously. The aim of our study was to design a skin chamber, in which tumor vascularization could be imaged non-invasively with both, MRI and optical imaging in the same tumor model.
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